445 research outputs found

    A performance evaluation of pruning effects on hybrid neural network

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    In this paper, we explore the pruning effects on a hybrid mode sequential learning algorithmnamely FuzzyARTMAP-prunable Radial Basis Function (FAM-PRBF) that utilizes FuzzyARTMAP to learn a training dataset and Radial Basis Function Network (RBFN) to performregression and classification. The pruning algorithm is used to optimize the hidden layer ofthe RBFN. The experimental results show that FAM-PRBF has successfully reduced thecomplexity and computation time of the neural network.Keywords: pruning; radial basis function network; fuzzy ARTMAP

    Future Frontiers in Organic Synthesis

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    The role of organic synthesis to the mankind is of paramount importance since the early nineteen century [1]. In 1828, Friedrich Wöhler discovered the synthesis of urea from ammonium cyanate, marking the starting point of modern organic synthesis. Wöhler concluded to his mentor Jöns Jacob Berzelius, "I cannot, so to say, hold my chemical water and must tell you that I can make urea without thereby needing to have kidneys, or anyhow, an animal, be it human or dog". Since then, organic synthesis has become an indispensable tool in industries such as petrochemicals, pharmaceutical, flavors, fragrances, agrochemical, and others. This is evident by the number of Nobel prizes awarded to organic chemists. The Nobel Prize in Chemistry 2001 was awarded to William S. Knowles, Ryoji Noyori, and K. Barry Sharpless for their work in asymmetric synthesis. This was followed by the award of the Nobel Prize in Chemistry 2005 to Yves Chauvin, Robert H. Grubbs and Richard R. Schrock "for the development of the metathesis method in organic synthesis". And just recently, Richard F. Heck, Ei-ichi Negishi and Akira Suzuki won the Nobel Prize in Chemistry 2010 for “palladium-catalyzed cross couplings in organic synthesis”

    Non-orthogonal multiple access for unmanned aerial vehicle assisted communication

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    The future wireless networks promise to provide ubiquitous connectivity to a multitude of devices with diversified traffic patterns wherever and whenever needed. For the sake of boosting resilience against faults, natural disasters, and unexpected traffic, the unmanned aerial vehicle (UAV)-assisted wireless communication systems can provide a unique opportunity to cater for such demands in a timely fashion without relying on the overly engineered cellular network. However, for UAV-assisted communication, issues of capacity, coverage, and energy efficiency are considered of paramount importance. The case of non-orthogonal multiple access (NOMA) is investigated for aerial base station (BS). NOMA's viability is established by formulating the sum-rate problem constituting a function of power allocation and UAV altitude. The optimization problem is constrained to meet individual user-rates arisen by orthogonal multiple access (OMA) bringing it at par with NOMA. The relationship between energy efficiency and altitude of a UAV inspires the solution to the aforementioned problem considering two cases, namely, altitude fixed NOMA and altitude optimized NOMA. The latter allows exploiting the extra degrees of freedom of UAV-BS mobility to enhance the spectral efficiency and the energy efficiency. Hence, it saves joules in the operational cost of the UAV. Finally, a constrained coverage expansion methodology, facilitated by NOMA user rate gain is also proposed. Results are presented for various environment settings to conclude NOMA manifesting better performance in terms of sum-rate, coverage, and energy efficiency

    Charging management protocol for near field communication charging

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    The current multiplicity of mobile communication devices has provided an impetus for the research into new mechanisms to supplement battery charge. Wireless charging is a solution that serves to eliminate the cable requirements of typical battery charging implementations. Numerous wireless charging implementations are based on inductive coupling, similar to existing non-radiative short range communication systems. This study proposes incorporating a charge management protocol into the existing Near Field Communication Interface and Protocol-1 (NFCIP-1) specification to achieve NFC-enabled wireless charging. To this end, the original NFCIP-1 protocol has been modified through a time-sharing arrangement to support a charging task within the protocol cycle. Simulations of the modified protocol cycle were implemented using an appropriate battery model and charging algorithm. Numerical results show that the modified protocol is able to charge the target battery with minimum communication overhead. Satisfactory performance is also observed for charging up to 2 target devices in a single session

    Evacuation of the Pleural Cavity With an Infant Feeding Catheter Following en Bloc Resection of Hepatocellular Carcinoma and Involved Diaphragm–an Institutional Experience

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    En bloc resection of hepatocellular carcinoma and the involved diaphragm will, towards the end of operation, require evacuation of the pleural cavity, usually with a chest drain. We describe our method and experience of evacuating the pleural cavity, at the time of diaphragmatic repair, with an infant feeding catheter without the need of a chest drain. We have found the method safe and efficacious

    Indoor path loss model for 4G wireless network at 2.6 GHz

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    In this paper, a short-range, narrowband indoor propagation at 2.6 GHz was measured and modeled. The measurement campaign was conducted to characterize the path loss (PL) of Radio frequency (RF) at the Razak School building corridor. The corridor has unique structure and segmented in different sections. The irregular structure of corridor, further with various interior material used gives the unique characterization to the received power. The research work made in this paper is predominately targets to characterizing radio link of 2.6 GHz frequency in typical indoor corridor

    Compact circularly polarized truncated square ring slot antenna with suppressed higher resonances

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    This paper presents a compact circularly polarized (CP) antenna with an integrated higher order harmonic rejection filter. The proposed design operates within the ISM band of 2.32 GHz± 2.63 GHz and is suitable for example for wireless power transfer applications. Asymmetrical truncated edges on a square ring create a defected ground structure to excite the CP property, simultaneously realizing compactness. It offers a 50.5% reduced patch area compared to a conventional design. Novel stubs and slot shapes are integrated in the transmission line to reduce higher (up to the third) order harmonics. The proposed prototype yields a -10 dB reflection coefficient (S11) impedance bandwidth of 12.53%, a 3 dB axial ratio bandwidth of 3.27%, and a gain of 5.64 dBi. Measurements also show good agreement with simulations. © 2017 Sabran et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

    Safety and efficacy of human Wharton's Jelly-derived mesenchymal stem cells therapy for retinal degeneration

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    Purpose To investigate the safety and efficacy of subretinal injection of human Wharton’s Jelly-derived mesenchymal stem cells (hWJ-MSCs) on retinal structure and function in Royal College of Surgeons (RCS) rats. Methods RCS rats were divided into 2 groups: hWJ-MSCs treated group (n = 8) and placebo control group (n = 8). In the treatment group, hWJ-MSCs from healthy donors were injected into the subretinal space in one eye of each rat at day 21. Control group received saline injection of the same volume. Additional 3 animals were injected with nanogold-labelled stem cells for in vivo tracking of cells localisation using a micro-computed tomography (microCT). Retinal function was assessed by electroretinography (ERG) 3 days before the injection and repeated at days 15, 30 and 70 after the injection. Eyes were collected at day 70 for histology, cellular and molecular studies. Results No retinal tumor formation was detected by histology during the study period. MicroCT scans showed that hWJ-MSCs stayed localised in the eye with no systemic migration. Transmission electron microscopy showed that nanogold-labelled cells were located within the subretinal space. Histology showed preservation of the outer nuclear layer (ONL) in the treated group but not in the control group. However, there were no significant differences in the ERG responses between the groups. Confocal microscopy showed evidence of hWJ-MSCs expressing markers for photoreceptor, Müller cells and bipolar cells. Conclusions Subretinal injection of hWJ-MSCs delay the loss of the ONL in RCS rats. hWJ-MSCs appears to be safe and has potential to differentiate into retinal-like cells. The potential of this cell-based therapy for the treatment of retinal dystrophies warrants further studies
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